In a dystopia overrun by corruption, crime, and cybernetic implants, an impulsive but talented street kid named David, after losing everything he has in a drive-by shooting, makes the choice to survive on the wrong side of the law as an "edgerunner": a high-tech, black-market mercenary also known as a "cyberpunk".
A boy in modern-day Japan desires to be a mastermind who exerts power from the shadows, but in the process of training, gets hit by a truck and dies. He is reborn in a fantasy world as Cid Kagenou, where he maintains a perfectly mediocre appearance so as to not stand out and pursue his dream of manipulating from the shadows. One day, he stumbles upon an elven girl infected by a mysterious disease and cures her.
Lonely thirty-seven-year-old Satoru Mikami is stuck in a dead-end job, unhappy with his mundane life, but after dying at the hands of a robber, they awaken to a fresh start in a fantasy realm... as a slime! As Rimuru acclimates to their new, goopy, existence, their exploits with the other monsters set off a chain of events that will change the world forever!